Participate in AI4Life’s Denoising Challenge


Published July 9, 2024

The AI4Life project, coordinated by Euro-BioImaging, is happy to announce the launch of the first AI4Life challenge, which aims to improve denoising techniques for microscopy images. Join the challenge now and submit your solutions by July 31st.

AI4Life Denoising Challenge 2024

What is the challenge about?

Microscopy images are crucial for scientific research, particularly in biology and medicine. However, these images often suffer from various types of noise introduced during the image acquisition process, which can degrade the quality of the images and significantly complicate their interpretation. Denoising microscopy images is, therefore, essential to improve image quality, all the while preserving important features such as edges, textures, and fine details.

In recent years, deep learning algorithms emerged as a successful approach to removing noise while retaining useful signals. Unlike classical algorithms, which use defined mathematical functions to remove noise, deep learning methods learn to denoise from example data, providing a powerful content-aware approach. Deep learning denoising is already assisting many researchers with analysing their acquired images and significantly improves the quality of downstream deep learning approaches such as segmentation or classification.

Aim of the challenge

The challenge’s focus is an unsupervised denoising task, which is particularly complex and key for the bioimage community. Unlike supervised learning, which requires pairs of noisy and clean images, unsupervised learning is a training process based on using only noisy images, making it a more accessible approach given the difficulty and labour-intensive nature of paired dataset acquisitions.

In this challenge, AI4Life invites researchers to apply their deep learning algorithms to four datasets featuring two types of noise: structured and unstructured. The aim is to compare the performance of both existing denoising methods and novel ones.

Why should you participate?

  • Get access to and gain experience with real-world annotated biomedical data
  • Improve your machine learning skills
  • Compare and benchmark your own models to those of others and state-of-the-art algorithms
  • Contribute to solving real-world image analysis problems to help advance biomedical research
  • Connect with our AI4Life experts and become part of the AI4Life community
  • Winning models will be shared and available for reuse on the BioImage Model Zoo, AI4Life’s model repository for bioimage analysis

The AI4Life project

AI4Life is a Horizon Europe-funded project that brings together the computational and life science communities. The project’s goal is to empower life science researchers to harness the full potential of Artificial Intelligence and Machine Learning methods for bioimage analysis by providing services, and developing standards aimed at both developers and users. Find out more on the project website.

Go to Challenge

More news from Euro-BioImaging

December 19, 2025

We're Hiring: Scientific Project Manager

Location: Turku, Finland (Euro-BioImaging ERIC Statutory Seat)Full-time position | Fixed term until 30 April 2028 | Gross Salary: €3,500–€5,000/month Be at the centre of…

SCIANCE Project Logo White

December 18, 2025

SCIANCE selected to support RAISE as the European Commission launches new AI science initiative

The European Commission recently launched the Resource for AI Science in Europe (RAISE) at the AI in Science Summit held in Copenhagen in early…

Diego at the entrance of Integrated Microscopy Technologies at SciLifeLab in Stockholm (Sweden).

December 17, 2025

Learning Expansion Microscopy at Swedish NMI

Diego Ramirez is a microscopy specialist helping users with optical microscopy techniques at the Biophysika Unit, part of the Euro-BioImaging’ Bilbao Node. Ana…